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Technology

Each additional cup of coffee associated with a 10% lower risk of diabetes

According to a new study by Harvard University, every extra cup of coffee you drink reduces the risk of diabetes by 10%, but the benefits are greatly reduced by adding sugar Type 2 diabetes (T2D) is a common chronic disease that affects more than 540 million people worldwide. With the change of living and eating…

Technology

Semaglutide is making waves again

Recently, the action of Semaglutide has been updated frequently. Nutrition Review published an article this year titled “What is the new ingredient (① |)? Semaglutide is mainly used to reduce blood sugar, but because the ingredient has a certain effect of suppressing appetite, it is suitable for weight loss among people. According to the reporter,…

Technology

Engineering yeast broke through bottleneck of Brazilian green propolis and produced atipyrine C

Universities jointly use engineered yeast to break through the production bottleneck of Brazil’s green propolis active ingredient, and record production of atipyrine C Brazilian green propolis is a natural product with rich medicinal value, and its main active ingredient, Artepillin C, has been confirmed in a number of studies with anti-inflammatory, antioxidant, antibacterial and anti-cancer…

Technology

Research frontiers and challenges of nucleic acid drugs

introduction The central law of genetics holds that nucleic acid carry human genetic information and play a vital role in life processes such as growth, development and reproduction, and that nucleic acids can be used to modify genetic information to treat various diseases. Nucleic acid drugs (NAD) are a class of gene therapy drugs based…

Research frontiers and challenges of nucleic acid drugs

gshworldJanuary 13, 2025January 13, 2025022 mins

Deep learning for NAD/NADP cofactor prediction and engineering using transformer attention analysis in enzyies

NAD/NADP cofactor prediction and engineering using Transformer in enzyme

gshworldDecember 26, 2024December 26, 202407 mins

Research background In nature, NAD(P) -dependent oxidoreductases are one of the most widely distributed enzymes, and they play an important role in the energy metabolism and REDOX reaction of organisms. NAD(P) acts as a cofactor for these enzymes, and its specificity (that is, the enzyme’s selectivity for NAD or NADP) is critical for the enzyme’s…