NAD/NADP cofactor prediction and engineering using Transformer in enzyme
Research background In nature, NAD(P) -dependent oxidoreductases are one of the most widely distributed enzymes, and they play an important role in the energy metabolism and REDOX reaction of organisms. NAD(P) acts as a cofactor for these enzymes, and its specificity (that is, the enzyme’s selectivity for NAD or NADP) is critical for the enzyme’s…