Health benefits of glutathione

Health benefits of glutathione

Glutathione is an active tripeptide formed by the condensation of glutamic acid, cysteine and glycine by peptide bond. GSH is widely found in animal liver, blood, yeast and wheat germ, and a small amount is also distributed in plant tissues such as vegetables. Glutathione has unique physiological functions and is known as longevity factor and…

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The glutathione S-transferase Gsttl drive ssurvival and dissemination in metastases

Novel mechanism of tumor metastasis mediated by glutathione S-transferase Gstt1

Recently, Raul Mostoslavsky’s team, from Harvard Medical School in The US, published a paper online in Nature Cell Biology entitled “The glutathione S-transferase Gstt1 drives survival and Survival” dissemination in metastases is to carry out RNA sequencing (RNA-SEQ) and subsequent lost-function shRNA targeting for matched primary and metastatic solid tumors from PDAC and breast cancer…

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Autoregulatory control of mitochondrial glutathione homeostasis

Feedback regulation mechanism of glutathione balance in mitochondria

Glutathione is an important antioxidant in cells and plays an important role in cellular iron metabolism and detoxification of allogenic substances. Metabolic processes in cells are constantly influenced by various environmental factors. Many small metabolites (such as amino acids, certain coenzymes, and metal ions) need to be maintained at appropriate physiological concentrations to ensure normal…

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Glutathione

The antioxidant glutathione

Glutathione is an important antioxidant in the human body, in the form of reduced glutathione (GSH) and oxidized glutathione (GSSG), of which GSH is composed of glutamic acid, glycine and cysteine through peptide bonding, and is synthesized in the liver in the largest amount. Glutathione has many physiological functions 1, Antioxidant effect Free radicals can…

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Activation of glutathione metabolism through mitochondrial autophagy promotes hair regeneration

Activation of glutathione metabolism through mitochondrial autophagy promotes hair regeneration

On August 1, 2024, Professor Lei Mingxing team of Chongqing University published a comprehensive TOP journal Research (District 1, Chinese Academy of Sciences, IF=11) publish an article entitled Mitophagy Promotes Hair Regeneration by Activating Glutathione Metabolism, It was found that mitochondrial autophagy promoted the proliferation of hair embryo (HG) cells by regulating glutathione (GSH) metabolism….

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Modified Escherichia coli produced record glutathione

Modified Escherichia coli produced record glutathione

Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine and glycine that has a wide range of applications in the pharmaceutical, food and cosmetic industries. At present, traditional industrial production methods mainly rely on yeast fermentation process to synthesize, but this process has some limitations, GSH will accumulate in yeast cells, and the extraction…

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Glutathione precursors are a potential treatment for mental stress

Glutathione precursors are a potential treatment for mental stress

How to treat stress-related psychological disorders has always been an important research topic in the field of life science. Recently, an authoritative study revealed the role of glutathione precursors in the treatment of stress-related mental disorders. Chronic stress not only increases the risk of psychological disorders such as anxiety and depression, but is also a…

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