NMN improves vascular endothelial function Promote nitric oxide synthesis Nitric oxide produced by vascular endothelial cells is an important signaling molecule, which can regulate the dilation and contraction of blood vessels and maintain the normal tension of blood vessels. NMN NMN can promote nitric oxide synthesis by increasing the level of intracellular NAD+ and activating…
NMN can protect human corneal epithelial cells with high glucose, improve survival rate, improve mitochondrial function, promote migration, inhibit apoptosis, and restore tight connections, providing a new idea for the treatment of diabetes-related keratopathy. Diabetes mellitus (DM), as an increasingly common metabolic disease worldwide, has a serious impact on the quality of life of patients….
What is glutathione? Glutathione is the main antioxidant in the body and therefore plays an important role in controlling oxidative stress in the body. It is mainly composed of three amino acids, including cysteine, glycine and glutamic acid. Since it is an antioxidant, reduced glutathione (GSH) is its active form, which neutralizes free radicals and…
Glutathione’s amazing bioactive tripeptide Glutathione (GSH) is a bioactive tripeptide made from the dehydrated condensation of L-glutamic acid, glycine, and L-cysteine by peptide bonding. First discovered by Hopkins in 1921, glutathione contains a large number of gamma-glutamyl and sulfhydryl bioactive groups. Reduced form (GSH) and oxidized form (GSSG) are the two forms of glutathione that…
In recent years, scientific research has found that a substance called NMN (β-nicotinamide mononucleotide) has shown great potential in reversing intestinal aging. As the main digestive organ and the largest immune organ of the human body, the health of the gut is directly related to our overall physical and mental health. With the increase of…
NAD+ plays an integral role in the biology of aging. In today’s society, aging has become a risk factor for many diseases, including diabetes, cancer, cardiovascular disease, neurodegenerative diseases, and complications following infections such as COVID-19. Because of this, the scientific community is increasingly focusing on the effects of the physiology of aging and seeking…
What is NMN? What does NMN do? NMN is an inherent substance in the human body, also rich in some fruits and vegetables, it is widely involved in a number of biochemical reactions in the human body, is also the composition of NAD+ (nicotinamide adenine dinucleotide) raw material. By supplementing NMN to improve the level…
Adenosylmethionine is a potential agent in the treatment of ALD, and its mechanism is worth further investigation. Alcoholic liver disease (ALD) is a series of liver diseases caused by long-term heavy alcohol consumption. In the course of its pathogenesis, a variety of complex pathophysiological mechanisms are involved. Intestinal flora and endotoxin changes in alcoholic liver…
yesterday, Ke Li and Zhuorong Li, Institute of Medical Biotechnology, Chinese Academy of Medical Sciences, jointly published a paper “Adipocyte-derived glutathione promotes obesity-related breast cancer by Cell metabolism” regulating the SCARB2-ARF1-mTORC1 complex “, which discovered the role of glutathione (GSH) in obesity-related breast cancer. Obesity is an important risk factor for breast cancer, however the…
What is NMN? NMN, full name Nicotinamide Mononucleotide, is a natural compound found in all living cells and is a derivative of vitamin B3 (niacin). NMN plays a key role in cellular energy metabolism and is a precursor to NAD+ (nicotinamide adenine dinucleotide). As we age, levels of NAD+ gradually decline, which has been linked…
