The essential anti-aging tonic for staying up late: the combined effect of NMN and resveratrol
Staying up late, a common phenomenon in modern life, is quietly overdrawing our health.
Maybe you’ve wondered, “Will staying up late accelerate aging?” Is there anything I can do to combat this damage?”
How can staying up late accelerate aging?
Biological clock disorder: The body’s “metronome” is out of whack
The destruction of the biological clock by staying up late is one of the main factors that accelerate aging.
Our bodies have a precise “clock system” that regulates hormones such as melatonin and cortisol to maintain metabolic balance and immune function.
Staying up late will disrupt this rhythm, reduce melatonin secretion, and lead to poor sleep quality.
Long-term, may indirectly lead to telomere shortening (one of the markers of cellular aging), accelerate the aging process.
Hint: Although the direct link between circadian clock disruption and telomere shortening is still being studied, chronic inflammation and oxidative stress triggered by staying up late may be an important bridge.
Increased oxidative stress: the process by which the body “rusts”
Staying up late significantly increases the production of free radicals in the body.
These free radicals act like “rust” in the body, attacking important structures such as DNA, proteins and cell membranes.
If the antioxidant system is unable to remove these free radicals in time, the body is prone to chronic damage, leading to accelerated aging.
Decreased immunity: Compromised guard system
Lack of sleep weakens the function of the immune system, inhibits the activity of T cells and natural killer cells, and increases the secretion of inflammatory factors.
Not only does this inflammatory state make you more susceptible to colds, it can also be a driver of aging and chronic disease.
Intuitive impact on appearance
Staying up late will lead to reduced skin collagen synthesis, damaged skin barrier, and decreased repair ability, manifested as skin sagging, darkening, dark circles and even early wrinkles.
It can be said that staying up late is the number one enemy of beauty.
How do NMN and resveratrol combat late night damage?
NMN and resveratrol are the two “stars” that have been hotly discussed in recent years.
Scientific research has found that certain supplements may help alleviate the damage of staying up late.
NMN: A potential tool for cellular energy repair
NMN (nicotinamide mononucleotide) is a precursor to NAD+, which is an important coenzyme in cellular energy metabolism and DNA repair and is gradually reduced during aging.
Staying up late can further accelerate this loss.
The mechanism of NMN:
- Increase NAD+ levels, promote mitochondrial function, and help cells restore energy metabolism.
- Activation of DNA repair mechanisms may delay telomere shortening.
- Research progress: Animal experiments show that NMN can significantly improve metabolic function and delay aging.
However, it should be noted that human trials are still in the preliminary stage, and the actual effects vary from person to person.
Resveratrol: The natural “antioxidant guardian”
Resveratrol is a polyphenolic compound found in natural foods such as grape skins and red wine.
It is involved in antioxidant and anti-inflammatory responses by activating the SIRT1 (longevity gene) pathway.
Mechanism of action of resveratrol
- Antioxidant: Neutralizes free radicals and reduces cell damage.
- Anti-inflammatory: Reduce the level of inflammatory factors, improve the chronic inflammation caused by staying up late.
- Improve metabolism: regulate fat metabolism and reduce the risk of obesity caused by staying up late.
Research progress: In animal experiments, resveratrol showed significant anti-aging effect.
But in human trials, the effect has not been fully established due to the low bioavailability of resveratrol.
Scientific advice: A combination of supplements suitable for staying up late
For people who often stay up late, scientific supplements can help repair the body to a certain extent, but can not replace healthy living habits.
Basic recommendation: NMN + resveratrol
Recommended dosage:
NMN: 250-500mg daily (recommended for fasting in the morning).
Resveratrol: 100-300mg daily (with fat food, absorption effect is better).
Functions:
Increase NAD+ level and repair cell energy metabolism.
Reduce free radicals and relieve chronic inflammation caused by staying up late.
Enhancing combination: NMN + Coenzyme Q10 + Vitamin C
Suitable for people: People with strong fatigue and decreased immunity after staying up late.
Recommended dosage:
NMN: 250-500mg.
Coenzyme Q10:30-100mg daily (with meals).
Vitamin C: 500-1000mg daily.
Functions:
Coenzyme Q10 is directly involved in energy metabolism and improves energy.
Vitamin C boosts immunity and improves skin condition.
Full protection: Resveratrol + Omega-3 + Vitamin E
Suitable people: worry about cardiovascular health, skin problems stay up late party.
Recommended dosage:
Resveratrol: 100-300mg.
Omega-3:250 to 500mg.
Vitamin E: 100-400IU daily.
Functions:
Omega-3 improves cardiovascular function.
Vitamin E further enhances antioxidant capacity and works synergistically with resveratrol.
How to choose effective NMN and resveratrol products?
NMN Purchase Guide
Purity: Select high purity products above 99%.
Formula: Preferably compound formula containing coenzyme Q10, lipoic acid and other synergistic ingredients.
Certification: Check whether the product has been tested by an authoritative third party to ensure the safety of the ingredients.
Resveratrol shopping guide
Concentration: 100-300mg per capsule, low dose may have limited effect.
Form: Choose fat-soluble resveratrol products (such as the form of combined phospholipids) to improve absorption.
Packaging: Use products designed to avoid light and moisture to ensure the stability of ingredients.
Formal channels are key
Whether NMN or resveratrol, its recommended to buy through regular channels, check the product ingredient list and test report, and avoid buying miscellaneous or shoddy products.
Conclusion
It is true that the damage to health of staying up late cannot completely avoided, but through scientific supplement selection, you can help alleviate some aging and damage.
These supplements can only play a supporting role, regular sleep and healthy diet is the foundation of anti-aging.
References:
- Nadeeshani H, Li J, Ying T, Zhang B, Lu J. Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns. J Adv Res. 2021 Aug 11;37:267-278. doi: 10.1016/j.jare.2021.08.003IF: 11.4 Q1 . PMID: 35499054; PMCID: PMC9039735.
- Hecker A, Schellnegger M, Hofmann E, Luze H, Nischwitz SP, Kamolz LP, Kotzbeck P. The impact of resveratrol on skin wound healing, scarring, and aging. Int Wound J. 2022 Jan;19(1):9-28. doi: 10.1111/iwj.13601. Epub 2021 May 5. PMID: 33949795; PMCID: PMC8684849.
