NMN has been dubbed the “elixir of life”, but with the major media and false rumors, watching this “anti-aging” rising star is about to fall.
So NMN is false, refuting rumors is wrong, or deserved?
In order to distinguish between true and false miracle drugs, we must first understand the nature of NMN.
Who is NMN?
In fact, NMN can called as a derivative of vitamin B group, the full name of nicotinamide mononucleotide, is the precursor of the cofactor NAD+ of longevity protein in human body, and its function mainly reflected by NAD+.
NAD+ is an indispensable coenzyme component of hundreds of enzyme proteins in the human body, including longevity enzyme proteins, which plays a fundamental role in human health.
However, with the increase of age, the content of NAD+ in the human body gradually decreases, the communication between mitochondria and nucleus damaged, and the reduction of NAD+ also damages the ability of cells to produce energy.
This may be why we get old and sick.
Simply put, NMN is a vitamin B derivative that is inherent in our bodies.
Seemingly a hundred miles of harmless NMN, but why is it being false refuted rumors, flying all over the world?
The reason for being denied rumors, being beaten.
On the one hand, when people accept some new things, they are always in a kind of defensive psychology due to lack of contact or understanding.
On the other hand, some bad businesses seem to smell business opportunities, in order to grasp the psychology of the public, at the expense of gimmicks, rumors, in an attempt to mislead the majority of consumers.
Aside from the efficacy of NMN for the time being, the following collated the various rumors circulating on the Internet, hoping to help the melon eaters understand the most real side of NMN.
NAD+ can directly supplemented?
NMN function is reflected through NAD+, so why not take NAD+ directly?
Because the NAD+ molecule relatively large, its difficult for NAD+ supplemented by oral administration to penetrate the cell membrane and enter the cell interior to have an effect on the human body.
That’s why scientists are starting with NAD’s precursors to boost our levels of NAD+.
Compared with other NAD+ supplementation methods, NMN bypasses the bottleneck of NAMPT rate-limiting enzymes and can quickly supplement NAD+ in the body, which is the best and most direct supplement method.
Therefore, the effect of products known as NAD+ direct supplements on the human body can said to minimal, and consumers must sharpen their eyes and carefully distinguish when buying.
‘Miracle medicine’ makes people live to 150?
According to a report in the Australian Daily Mail, “Australia has developed the ‘elixir of youth’ that can extend life to 150 years!” Old news, all over the Internet.
In response to a subsequent article suggesting that 150 is a bit overstated, researchers in David’s Lab at Harvard Medical School confirmed that 150 is a translation error, but dismissed the report as a bit of an overcorrection. 150 is a number derived from a combination of anti-aging studies.
Taking NMN may promote cancer?
An article suggesting taking NMN or promoting cancer posted on social media, causing a lot of misunderstanding.
But a moment’s thought by anyone with basic scientific knowledge shows that this argument is completely untenable:
NAD is a key factor that all cells need to survive, and switching the experiment to glucose will feed cancer cells as well, can it said that glucose causes cancer?
The experiment only carried out a single culture of a specific cancer cell, completely ignoring the real protective function of NAD for the body’s immune system to repair DNA.
NAD is the body’s own substance, we know that the content of NAD in young people is much higher than that of the older people, according to the theory of the article, the incidence of cancer in young people will be much higher than that of the older people.
On the contrary, a large number of studies in top journals such as Nature, Science and Cell have confirmed that the reduction of NAD+ levels induces cancer, and now clinical trials have thoroughly proven the safety and effectiveness of NMN.
NMN after 5 years Come into market?
In fact, there is a certain misunderstanding! NMN sold in the market belongs to Dietary Supplement (food supplement), which is a food standard.
Dr. David Sinclair and DR.Lindsay Wu said that NMN, which will be available in five years, is an anti-aging drug and is the drug standard!
The drug has to go through a clinical trial of 1/2/3, the time is relatively long, and the NMN for pharmaceutical use listed after five years.
It is gratifying that on February 19, 2024, Japan released the interim report of the clinical trial of “Long-term (24 weeks) oral NMN benefits on human beings”, which is the first clinical confirmation in the world:
After oral administration of NMN, the expression of longevity protein increased, and the expression of many types of hormones also increased, and it may help cure cancer. NMN as a drug standard is not far away.
NMN Cost Cabbage Price?
Some reports point out that the cost of the more expensive NMN is only a few cents, and the unknown people also sigh that such a high “IQ tax” can only paid by the rich, is this really the case?
According to the survey, the quotation of 500mg NMN on the world’s largest reagent website Sigma-Aldrich is 11321 yuan, and it is out of stock, that is to say, the price of 1g is 22,641 yuan, and a few cents a gram is 100,000 times different
Although Japan conquered the fermentation technology of NMN in 2015, the general price of 3000mg NMN is now about 5000, and the price of 9000mg even reaches 20,000 yuan.
NMN, NA, NAM, and NR are all precursors of NAD+ and have very similar names.
NA, NAM and NR are very cheap, but the conversion into NAD+ is very inefficient and has high side effects.
Only in terms of name, these four types of substances are easy to confuse even people in the industry, so there is a rumor of NMN a few cents.
As NMN recognized by more and more consumers, unscrupulous merchants take advantage of this difference to sell large doses of NA, NAM, NR and other products under the banner of NMN, but they do not know that overdose of these precursors with similar names has certain side effects.
So here to remind the majority of consumers, in the purchase of NMN related products, must pay attention to polish their eyes, carefully distinguish, do not buy some shoddy or counterfeit products, in order to prevent adverse effects on the body.
NMN removed due to quality issues?
Some consumers therefore doubt its quality, the relevant person in charge said: enzymatic process has made NMN mass production, will make the cost of NMN drop again, really make NMN fly into the homes of ordinary people.
Of course, immortality has always the dream of human beings, and whether it can reach 150 years old needs to explored, but it is equally important to prolong life, and healthy living should the ultimate goal of life that we pursue!
7 Rumors about NMN/NAD+, do you believe them?
Which rumors about NMN/NAD+ do you believe?
What exactly is NMN, which has swept up in the circle of friends and rumors?
Who is NMN, which is widely rumored?
What should NMN, the “immortality” drug that has beaten and refuted by false rumors, do?
Is NMN sublingual better?
Recently, it has reported that oral NMN cannot enter the brain through the blood, and the efficiency of biological drugs is very low, so it is necessary to take the sublingual passage through the sublingual to allow the body to absorb quickly, which 3 to 10 times larger than the oral way.
But is this really the case?
Through literature review, we found that NMN supplementation can significantly increase the level of NAD+ in the brain, and the news that NMN cannot enter the brain through the blood is purely a rumor.
In this regard, we would like to ask, if NMN cannot pass the blood-brain barrier, how will Alzheimer’s disease improved?
Why would such a statement spread?
Its possible that the main ingredient of NMN products sold by bad merchants some unknown ingredient digested by the stomach, rather than NMN, in order to mislead consumers to buy NMN sublingual tablets.
Immortality has always been the dream of human beings. Whether NMN can make us live to 150 years old still needs to explored.
Prolonging life is also important, healthy life should be the ultimate goal we pursue!
