Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine and glycine, which has cell protection, antioxidant, anti-aging, detoxification and other effects, and exists in almost every cell in the human body.
From a biochemical perspective, glutathione peroxidase is involved in many REDOX reactions. REDOX reactions play an important role in the following two aspects:
Protection of enzymes from endogenous and exogenous peroxides;
Binding, metabolizing and excreting toxic catabolites and heavy metals.
Most of the action of glutathione is manifested in the liver and has a protective effect on the liver.
Glutathione plays an important role in the body
Glutathione is an important antioxidant in the body, and levels of GSH in the body can be reduced by many factors, including poor nutrition, environmental toxins, and stress.
Its levels tend to decline with age. Increasing the body’s GSH has health benefits, including reducing oxidative stress, which can cause symptoms of many different chronic diseases, including autoimmune diseases.
antioxidant
Glutathione is one of the main antioxidants in the body, helping to scavenge free radicals.
Free radicals are a class of unstable molecules that can cause damage to cells and tissues, and GSH helps maintain cell structure and function by trapping free radicals. High levels of oxidative stress can be a precursor to a variety of diseases.
Anticancer, regulation of apoptosis
Glutathione can regulate apoptosis to maintain cell balance and prevent the growth and spread of abnormal cells.
An article in the Journal of Cancer Science and Therapy states that GSH deficiency can lead to elevated levels of oxidative stress, which may lead to cancer. Studies have also indicated that increased levels of glutathione can increase the antioxidant levels and the ability of cancer cells to resist oxidative stress.
Skin problem
Improve psoriasis.
Reduces cell damage from liver disease
A lack of antioxidants, including GSH, may exacerbate liver cell death.
Glutathione has been shown to improve blood malondialdehyde (a marker of liver cell damage) and bilirubin levels in liver patients. Oral GSH has a positive effect on patients with fatty liver.
Reduce three high levels (cholesterol, blood pressure, lipids, blood sugar)
Relieve uterine, ovary, breast, thyroid nodules, fibroids, cysts and other problems
GSH can help the liver detoxify and metabolize excess body hormones. The liver is involved in the metabolism of several endocrine hormones, including sex hormones (estrogen, progesterone, androgens), thyroid hormones, glucagon-like peptide-1 (secretion of insulin), and steroid hormones (stress hormones cortisol, adrenaline, cholesterol), and plays a role in the activation and deactivation of these hormones.
Participate in detoxification reactions of heavy metals, toxins, radioactive substances, etc
Glutathione binds to a variety of toxic substances and is involved in detoxification reactions within cells to help remove harmful substances from the body.
Improve insulin resistance caused by obesity
As we age, the body produces less GSH. Low tathione levels associated with less fat burning and higher rates of fat storage in the body.
Improve blood circulation and increase mobility in patients with peripheral artery disease
Peripheral artery disease occurs when peripheral arteries become clogged with plaque. It occurs most often in the legs, where GSH improves blood circulation and improves the ability to walk painless over long distances.
Reduces the symptoms of Parkinson’s disease
Parkinson’s disease affects the central nervous system, and GSH has a positive effect on symptoms such as tremors and stiffness.
Helps fight autoimmune diseases
Chronic inflammation caused by autoimmune diseases (Hashimoto, rheumatoid arthritis, celiac disease, lupus erythematosus, etc.) can increase oxidative stress. GSH protects cellular mitochondria by eliminating free radicals.
Improve immunity
Glutathione is essential for the proper functioning of the immune system. It is involved in the differentiation and activation of lymphocytes and helps maintain the vitality of immune cells.
Reduces oxidative damage in children with autism
Multiple studies have shown that children with autism have higher levels of oxidative damage and lower levels of GSH in their brains, which increases their susceptibility to neurological damage caused by substances such as mercury.
Reduces symptoms of respiratory disease
Glutathione helps thin mucus and also reduces inflammation.
Reduces ulcerative colitis damage
Glutathione supplementation may improve cell function in diseases such as ulcerative colitis and prevent further cell damage by preventing the harmful effects of oxidative stress.
Support against the REDOX cycle
By participating in the REDOX cycle, GSH helps reduce other oxidised antioxidants, such as vitamins C and E, returning them to antioxidant power.
anti-aging
Aging affects every cell in the body, and glutathione supplementation can play a positive role in reducing wrinkles, improving skin elasticity and regulating melanin production.
Why does the skin turn black
Skin cells are damaged, resulting in black/dark spots
Skin cell damage
The damaged skin cells are in a damaged state and stimulate the black/white cells to produce dark spots
Black dot generation
Black/su cells overproduce black spots catalyzed by tyrosine
blackspot
The accumulated black/affair forms local dullness and gradually evolves into black spots
Triple whitening combination formula: Glutathione + cysteine + vitamin C, white the whole body from the inside out.
How to choose a glutathione supplement form
Glutathione comes in two different forms:
Reduced glutathione (GSH, or 1-glutathione) (active form)
Oxidized glutathione [GSSG] (inactive form)
Reduced glutathione becomes oxidized and inactive in the cellular environment and becomes oxidized glutathione.
More than 90% of GSH in the human body is in the reduced form, and the rest is in the oxidized form. Glutathione oxidation and reductase catalyze the interconversion of the two. Due to the action of glutathione reductase, the oxidized form can recycled into reduced glutathione.
Reduced glutathione found in almost every cell in the human body. Its distribution is second only to that of water molecules. The biggest problem with GSH is its extremely low oral bioavailability.
Even when reduced glutathione is taken, it is still destroyed by powerful digestive enzymes in the small intestine and hydrolyzed, leaving behind three amino acids: glycine, glutamine and cysteine.
So that almost all oral GSH can not enter the blood circulation, can not enter the cell to do its job.
The technology of liposome and microphospholipid coating can better deliver GSH to the target, so as to exert its effectiveness.
Cleanse, liver, resistance support and antioxidant liquid GSH. GSH known as our body’s antidote and an ally of healthy aging, immunity and detoxification.
The antioxidant glutathione helps protect our cells from the negative effects of toxins, helping to neutralize and remove them. It can also support a balanced immune system.
Unparalleled absorption – The bioavailability of common glutathione supplements is poor, and liposome delivery organisms flood the body with nutrients and botanics when they reach the tongue and ingested.
reference
- [1] Huang Jin, Yang Guoyu, Li Hongji, et al. Research progress on the mechanism of antioxidant action [J]. Nature Journal,2004(02):74-78. (in Chinese)
- [2] Jia Zhen, Wang Dan, You Song. Research progress of glutathione [J]. Journal of Shenyang Pharmaceutical University,2009,26(03):238-242. (in Chinese)
- [3] Zhang Yi, Ye Sheng. Physiological function of reduced glutathione and its clinical application [J]. Chemistry of Life,20,40(12):2226-2235. (in Chinese)
- [4]Hayes J D, Flanagan J U, Jowsey I R. Glutathione transferases[J]. Annu. Rev. Pharmacol. Toxicol., 2005, 45: 51-88.
- [5]Ketterer B, Coles B, Meyer D J. The role of glutathione in detoxication[J]. Environmental health perspectives, 1983, 49: 59-69.
