Citicoline (CDP choline) : A nutrient that exists as a drug and supports the brain and nerves. 5 benefits + dose and side effects

Citicoline exists as a drug for nutritional support of the brain and nerves, 5 benefits + dose

Citicoline has been lauded for its cognitive enhancing properties in young and old people. Clinical studies have confirmed some of its boosting effects and revealed other unexpected benefits, but have also pointed out significant limitations. Read on for a final analysis of the benefits, dosage and safety of citicoline. What is citicoline? Citicoline (cytidine 5-diphosphate…

Read More
Health benefits of glutathione

Health benefits of glutathione

Glutathione is an active tripeptide formed by the condensation of glutamic acid, cysteine and glycine by peptide bond. GSH is widely found in animal liver, blood, yeast and wheat germ, and a small amount is also distributed in plant tissues such as vegetables. Glutathione has unique physiological functions and is known as longevity factor and…

Read More
The glutathione S-transferase Gsttl drive ssurvival and dissemination in metastases

Novel mechanism of tumor metastasis mediated by glutathione S-transferase Gstt1

Recently, Raul Mostoslavsky’s team, from Harvard Medical School in The US, published a paper online in Nature Cell Biology entitled “The glutathione S-transferase Gstt1 drives survival and Survival” dissemination in metastases is to carry out RNA sequencing (RNA-SEQ) and subsequent lost-function shRNA targeting for matched primary and metastatic solid tumors from PDAC and breast cancer…

Read More
Autoregulatory control of mitochondrial glutathione homeostasis

Feedback regulation mechanism of glutathione balance in mitochondria

Glutathione is an important antioxidant in cells and plays an important role in cellular iron metabolism and detoxification of allogenic substances. Metabolic processes in cells are constantly influenced by various environmental factors. Many small metabolites (such as amino acids, certain coenzymes, and metal ions) need to be maintained at appropriate physiological concentrations to ensure normal…

Read More
Glutathione

The antioxidant glutathione

Glutathione is an important antioxidant in the human body, in the form of reduced glutathione (GSH) and oxidized glutathione (GSSG), of which GSH is composed of glutamic acid, glycine and cysteine through peptide bonding, and is synthesized in the liver in the largest amount. Glutathione has many physiological functions 1, Antioxidant effect Free radicals can…

Read More
The more NMN you eat, the better?

The more NMN you eat, the better? Don’t blindly believe such words in the future!

NMN (beta-nicotinamide mononucleotide) has achieved compelling results in clinical trials as an oral supplement. Studies have shown that NMN supplements are able to significantly increase blood NAD+ concentrations in middle-aged healthy adults and have demonstrated excellent safety and tolerability. A randomized, multicenter, double-blind, placebo-controlled, concurrent cohort, dose-dependent clinical trial enrolled 80 middle-aged healthy adults and…

Read More
Activation of glutathione metabolism through mitochondrial autophagy promotes hair regeneration

Activation of glutathione metabolism through mitochondrial autophagy promotes hair regeneration

On August 1, 2024, Professor Lei Mingxing team of Chongqing University published a comprehensive TOP journal Research (District 1, Chinese Academy of Sciences, IF=11) publish an article entitled Mitophagy Promotes Hair Regeneration by Activating Glutathione Metabolism, It was found that mitochondrial autophagy promoted the proliferation of hair embryo (HG) cells by regulating glutathione (GSH) metabolism….

Read More