Recently, Raul Mostoslavsky’s team, from Harvard Medical School in The US, published a paper online in Nature Cell Biology entitled “The glutathione S-transferase Gstt1 drives survival and Survival” dissemination in metastases is to carry out RNA sequencing (RNA-SEQ) and subsequent lost-function shRNA targeting for matched primary and metastatic solid tumors from PDAC and breast cancer…
Glutathione is an important antioxidant in cells and plays an important role in cellular iron metabolism and detoxification of allogenic substances. Metabolic processes in cells are constantly influenced by various environmental factors. Many small metabolites (such as amino acids, certain coenzymes, and metal ions) need to be maintained at appropriate physiological concentrations to ensure normal…
Glutathione is an important antioxidant in the human body, in the form of reduced glutathione (GSH) and oxidized glutathione (GSSG), of which GSH is composed of glutamic acid, glycine and cysteine through peptide bonding, and is synthesized in the liver in the largest amount. Glutathione has many physiological functions 1, Antioxidant effect Free radicals can…
NMN has shown some potential in improving hair loss and grey hair. 1, NMN and hair loss Promote hair follicle cell growth: NMN promotes the growth and viability of hair follicle cells by increasing intracellular NAD+ levels. This helps to increase hair density, shorten hair growth cycles, and promote healthier hair morphology. The results of…
NMN (beta-nicotinamide mononucleotide) has achieved compelling results in clinical trials as an oral supplement. Studies have shown that NMN supplements are able to significantly increase blood NAD+ concentrations in middle-aged healthy adults and have demonstrated excellent safety and tolerability. A randomized, multicenter, double-blind, placebo-controlled, concurrent cohort, dose-dependent clinical trial enrolled 80 middle-aged healthy adults and…
On August 1, 2024, Professor Lei Mingxing team of Chongqing University published a comprehensive TOP journal Research (District 1, Chinese Academy of Sciences, IF=11) publish an article entitled Mitophagy Promotes Hair Regeneration by Activating Glutathione Metabolism, It was found that mitochondrial autophagy promoted the proliferation of hair embryo (HG) cells by regulating glutathione (GSH) metabolism….
Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine and glycine that has a wide range of applications in the pharmaceutical, food and cosmetic industries. At present, traditional industrial production methods mainly rely on yeast fermentation process to synthesize, but this process has some limitations, GSH will accumulate in yeast cells, and the extraction…
How to treat stress-related psychological disorders has always been an important research topic in the field of life science. Recently, an authoritative study revealed the role of glutathione precursors in the treatment of stress-related mental disorders. Chronic stress not only increases the risk of psychological disorders such as anxiety and depression, but is also a…
Citicoline sodium (C14H25N4NaO11P2) is composed of ribose, cytosine, phosphoric acid and choline. As an endogenous compound of human body, Citicoline sodium is an important medium for phospholipid synthesis in cell membrane, and also an external source for synthesis of acetylcholine. Acetylcholine is an important neurotransmitter and plays a very important role in nucleotide metabolism. Cerebral…
Glutathione is also known as a great discovery. It was discovered by an Englishman who was also under great stress. At the same time as Fleming, his name was Frederick Goland Hopkins, and his name is too long, let’s call it Hopkins. Glutathione was discovered before penicillin in 1921. Hopkins was very successful all his…
