Glutathione is a natural antioxidant that your body makes from three amino acids: glycine, L-cysteine, and L-glutamate. It helps protect your cells from damage caused by free radicals, toxins, and heavy metals. Glutathione also supports your immune system, energy production, and DNA repair.
Glutathione is an important antioxidant in cells and plays an important role in cellular iron metabolism and detoxification of allogenic substances. Metabolic processes in cells are constantly influenced by various environmental factors. Many small metabolites (such as amino acids, certain coenzymes, and metal ions) need to be maintained at appropriate physiological concentrations to ensure normal…
Glutathione is an important antioxidant in the human body, in the form of reduced glutathione (GSH) and oxidized glutathione (GSSG), of which GSH is composed of glutamic acid, glycine and cysteine through peptide bonding, and is synthesized in the liver in the largest amount. Glutathione has many physiological functions 1, Antioxidant effect Free radicals can…
On August 1, 2024, Professor Lei Mingxing team of Chongqing University published a comprehensive TOP journal Research (District 1, Chinese Academy of Sciences, IF=11) publish an article entitled Mitophagy Promotes Hair Regeneration by Activating Glutathione Metabolism, It was found that mitochondrial autophagy promoted the proliferation of hair embryo (HG) cells by regulating glutathione (GSH) metabolism….
Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine and glycine that has a wide range of applications in the pharmaceutical, food and cosmetic industries. At present, traditional industrial production methods mainly rely on yeast fermentation process to synthesize, but this process has some limitations, GSH will accumulate in yeast cells, and the extraction…
How to treat stress-related psychological disorders has always been an important research topic in the field of life science. Recently, an authoritative study revealed the role of glutathione precursors in the treatment of stress-related mental disorders. Chronic stress not only increases the risk of psychological disorders such as anxiety and depression, but is also a…
Glutathione is also known as a great discovery. It was discovered by an Englishman who was also under great stress. At the same time as Fleming, his name was Frederick Goland Hopkins, and his name is too long, let’s call it Hopkins. Glutathione was discovered before penicillin in 1921. Hopkins was very successful all his…
Glutathione is a short peptide composed of 3 amino acids that is present in almost every cell of the body and has two important antioxidant and integrated detoxification effects. Glutathione can help maintain the normal function of the immune system, and has an antioxidant effect, integrated detoxification effect, not only can used for drugs, but…
An authoritative study has revealed the therapeutic role of glutathione precursors in stress-related mental disorders. Chronic stress not only increases the risk of psychological disorders such as anxiety and depression, but is also a risk factor for neurodegenerative diseases (e.g., Parkinson’s disease, Alzheimer’s disease), metabolic disorders (e.g., large waist circumference, high blood pressure, diabetes), and…
Key research points Glutathione is an important tripeptide that is widely used in the pharmaceutical, food and cosmetic industries. In this paper, metabolic engineering of Escherichia coli (E. coli) was used to produce glutathione efficiently. Conventional glutathione is mainly produced by yeast fermentation, but the intracellular accumulation of yeast limits its production. The researchers significantly…
abstract Activated T cells produce reactive oxygen species (ROS), which trigger the antioxidant glutathione (GSH) response, which is essential for buffering elevated ROS and preventing cell damage. We report that glutathione is essential for T cell effector function by regulating metabolic activity. Conditional gene knockout of the catalytic subunit of glutamate-cysteine ligase (Gclc) blocks glutathione…
