What is S-adenosylmethionine?
S-adenosylmethionine (SAMe) may sound like a technical name, but it is a bright new star in pet nutrition.
As a highly efficient bioactive substance, it not only plays an important role in human health, but also has cleverly introduced into pet health products abroad.
S-adenosylmethionine discovered by the Italian scientist Cantoni in 1952, it a kind of adenosylmethionine triphosphate (ATP) and methionine in the cell through the methionine adenosyltransferase catalyzed synthesis, and then as a coenzyme to participate in the methyl-transfer reaction to lose a methyl group decomposition into S-adenosylhomocysteine.
S-adenosylmethionine plays an important role in transmethylation because of its “active methyl group”.
In higher organisms, more than 40 anabolic or catabolic chemical reactions involve the transfer of S-adenylyl methionine methyl groups to substrates such as nucleic acids, proteins, and fats, and ultimately, through biochemical reactions, to protect the liver, improve cognition, and many other functions.
S-adenosylmethionine benefits
1, Protect the liver
With the progress of pet medical treatment and the change of pet living environment, pet life has extended,
but at the same time, the incidence of liver diseases has gradually increased, especially in older people dogs and cats.
S-adenosylmethionine is a substance produced in the liver that plays an important role in transmethylation because of its “active methyl group”, which can play a role in liver protection, toxin elimination, and protein synthesis, making the pet’s hair thicker and shiny, and the eyes more bright and vivid.
2, Improve cognition
In this fast-paced era, keeping pets to accompany themselves has become the main choice of many urban white-collar workers,
but everyone is generally busy at work every day, plus a lot of social activities, and becomes unable to “take” time to get along with pets,
which leads to anxiety, depression and other problems in our small partners, and it happens that S-adenosylmethionine has a good effect in improving cognition.
In 1973, scientists found that S-adenosylmethionine can increase the content of 5′ -hydroxytryptamine and 5′ -hydroxyindoleacetic acid in the brain, which has a good effect on various depression.
S-adenosylmethionine has widely recognized by pet owners in the field of pet health products for many years:
S-adenosylmethionine action
In dogs, adding SAMe may also improve age-related mental deterioration. In humans, SAMe has also documented to have antidepressant effects.
S-Adenosylmethionine (SAMe) is an endogenous molecule that is synthesized by cells in the body and is part of a variety of biochemical pathways. SAMe is particularly important in liver cells because it plays an important role in metabolism.
S-adenosylmethionine application
It used as an adjunct to the treatment of liver diseases, especially liver diseases caused by acute hepatotoxins. SAMe has shown to increase glutathione levels in the liver. It is also used in animals treated with potentially hepatotoxic drugs over a long period of time.
In cats, SAMe may improve the outflow of bile. It may used to improve cognitive function in older people dogs. Antidepressant therapy for animals has not determined.
The safety of exogenous SAMe in pregnant animals has not demonstrated and should used with caution.
S-adenosylmethionine market future
Products containing S-adenosylmethionine are mainly pet health products, which have approved and widely used in America and Europe,
such as Denamarin, Denestra, SAMeLQ in the United States, NOVIFIT in France, etc.
At present, S-adenosylmethionine related products have not approved in China. Therefore, parents can only buy through wechat business or daigou.
However, due to the safety and authenticity of product purchasing, public recognition and the lack of relevant compliance procedures and other problems limit the large-scale promotion and application of S-adenosylmethionine products in China, so it is urgent to promote S-adenosylmethionine into the Chinese feed additives catalog as soon as possible and develop SAMe products more suitable for the Chinese market.
