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Mechanism of action of adenosylmethionine in alcoholic liver disease

Mechanism of action of adenosylmethionine in alcoholic liver disease

Adenosylmethionine is a potential agent in the treatment of ALD, and its mechanism is worth further investigation. Alcoholic liver disease (ALD) is a series of liver diseases caused by long-term heavy alcohol consumption. In the course of its pathogenesis, a variety of complex pathophysiological mechanisms are involved. Intestinal flora and endotoxin changes in alcoholic liver…

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Cell metabolism

Fat cells secrete glutathione to promote breast cancer

yesterday, Ke Li and Zhuorong Li, Institute of Medical Biotechnology, Chinese Academy of Medical Sciences, jointly published a paper “Adipocyte-derived glutathione promotes obesity-related breast cancer by Cell metabolism” regulating the SCARB2-ARF1-mTORC1 complex “, which discovered the role of glutathione (GSH) in obesity-related breast cancer. Obesity is an important risk factor for breast cancer, however the…

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NMN

What foods can supplement NMN?

What is NMN? NMN, full name Nicotinamide Mononucleotide, is a natural compound found in all living cells and is a derivative of vitamin B3 (niacin). NMN plays a key role in cellular energy metabolism and is a precursor to NAD+ (nicotinamide adenine dinucleotide). As we age, levels of NAD+ gradually decline, which has been linked…

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mitochondria

Mitochondria what? What effect does PQQ have on mitochondria?

introduction Mitochondria – this elementary school third grade textbook noun, still remember? Its main function is to synthesize ATP (adenosine triphosphate) through electron transfer and oxidative phosphorylation, which provides the energy necessary for the life activities of cells, and is the final oxidation of sugars, fats and amino acids and other substances to release energy….

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Engineering Escherichia coli for efficient glutathione production

Modified Escherichia coli produced record glutathione

What is glutathione? Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine and glycine that has a wide range of applications in the pharmaceutical, food and cosmetic industries. At present, traditional industrial production methods mainly rely on yeast fermentation process to synthesize, but this process has some limitations, glutathione will accumulate in yeast cells,…

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Nicotinamide Mononucleotide enhances fracture healing by promoting skeletal stem cell proliferation

Taking NMN promotes fracture healing

NMN promotes bone stem cell proliferation and helps fracture healing The research team recently published an article in the journal Theranostics showing that taking NMN significantly increases total NAD levels within callus to enhance cartilage callus formation and activate the regenerative potential of stem cells within bone. This finding highlights the relationship between NAD and…

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