NMN fights cliff aging
Aging is a gradual process, but not uniform, after research shows that the molecular level of aging of people and organisms has three obvious nodes, that is, there are three turning points of “cliff aging”, and suddenly feel different from before.
The research comes from neuroscientist Tony Wyss-Coray’s team at Stanford University in the US and Peter J. Campbell’s team at the Stem Cell Institute at the University of Cambridge in the UK
1. Three stages of cliff-like aging
Stage 1: Age 34
At this point, the changes in appearance are most obvious, such as reduced skin collagen, skin relaxation, muscle loss, and increased fine lines and spots.
And at this stage, it will obviously feel physical decline and lack of energy, and various sub-health problems will gradually appear, such as low immunity and poor sleep quality.
Stage 2: Age 60
Generally, we think that 60 years old and above is called the older people, one of the reasons is that aging is particularly obvious at the age of 60, not only in appearance, but also in behavior: walking speed slowed down, unable to exercise strongly, memory decline, easy to pant and so on.
Stage 3: Age 78
When you are 78 years old, you are already old, at this time, the reproduction and regeneration ability of cells is almost 0, the changes related to blood pathways and bone morphogenetic protein signal transduction are the most drastic, and various diseases of old age also hit, such as stroke, Alzheimer’s disease, cardio-cerebrovascular disease and so on.
2. Resist cliff aging: NMN
By increasing the level of “strongest coenzyme” NAD+, NMN activates longevity gene protein, repairs damaged aging mitochondria and DNA, thereby reversing body aging and restoring youthful vitality.
The significance of NMN and NAD+ for human body repair has already received the “stamp of approval” from six Nobel Prize winners in Medical post-biology.
David Sinclair, a tenured professor at Harvard Medical School, has found that NMN has a significant anti-aging effect, and he and his 80-year-old father are also taking it for a long time, with a biological age of 17 years younger!
With the increase of age, the level of NAD+ in the human body will become lower and lower, and the ability to generate NAD+ will become weaker and weaker, and the aging process will continue to accelerate. In particular, the level of NAD+ also declines in cliff-like aging at 34, 60, and 78 years of age.
In order to get the strongest anti-aging effect, it is necessary to take NMN in the critical period before, during and after the “cliff aging 3 nodes” to maintain a high level of NAD+, so as to delay the aging process and maintain the young state of the human body.
- When taken at age 34, it can improve the decline of skin and body function and maintain energy and vitality;
- Taking at the age of 60 can delay aging, maintain internal and external youth, and reduce the risk of a variety of middle-aged and older people diseases;
- When taken at the age of 78, it can improve the degenerative sexual health problems brought about by aging, such as enhancing vision, hearing and memory, improving sleep, maintaining various indicators of the body, and reducing the damage to the body from various diseases of old age.
3. The specific effects of NMN on human body
01 Anti-aging
With the increase of age, the level of NAD+ in the human body is constantly declining, resulting in a decline in human metabolism, accelerated aging, and a high incidence of various aging diseases.
Taking NMN can improve the level of NAD+, combat aging at the cellular level, activate cell energy level, awaken gene repair ability, delay or even reverse the occurrence of aging, and let the body return to a young state.
02 Repair damaged genes due to genetic errors
NMN improves the level of NAD+, which as a substrate can generate the gene repair enzyme PARP1. At the same time, the protein DBC1 can be separated from the inactive PARP1 to restore its activity and further improve the level of PARP1.
PARP1 can reprogram damaged or faulty genes according to the normal gene sequence to achieve the effect of repairing genes. This also reduces the risk of cancer.
03 More than 95% of the energy needed to produce the human body
NMN can be converted into NAD+, repair damaged mitochondria, activate mitochondrial energy, generate protein, fat and sugar, the three most important nutrients of the human body, and through the mitochondrial tricarboxylic acid cycle, meet the energy required for daily activities and metabolism of the human body. NAD+ is a very important energy “throttle”.
04 Prevention of three high, diabetes
Insulin is the key to lowering blood sugar. After NMN increases the level of NAD+, it can stimulate insulin activity and strengthen the breakdown of fats and polysaccharides in the body, so it can reduce the risk of diabetes.
05 Prevention and improvement of cardiovascular and cerebrovascular diseases
NMN can prevent and improve cardiovascular and cerebrovascular diseases through a variety of ways, such as increasing high-density lipoprotein, reducing low-density lipoprotein, antioxidant, reducing macrophage inflammation, reducing atherosclerotic plaque formation, stabilizing atherosclerotic plaque, reducing plaque rupture, improving blood flow, etc., to maintain cardiovascular and cerebrovascular health and stability.
06 Maintain capillary regeneration
The older the age, the lower the level of NAD+ in the body, the faster the rate of muscle loss, the less growth factors released, and the less growth factors received by the capillaries, which become fragile.
By increasing the level of NAD+, it can promote the production of longevity protein Sirtuin1 and maintain capillary regeneration.
07 Enhance body immunity
NMN has important immunomodulatory effects, which can promote the production of antibodies by spleen cells, enhance the function of immune T cells, and stimulate the production of immunoglobulin. At the same time, NMN can also reduce muscle tissue oxidation, reduce lactic acid accumulation, muscle soreness after exercise, and enhance the body’s energy metabolism.
08 Whitening and Moisturizing
NMN has strong antioxidant properties, so it is a potential photoprotective agent, which can prevent oxidative damage of cell membrane and mitochondrial membrane, repair photoaging caused by air pollution and ultraviolet radiation, reduce melanosis, and improve skin dullness, spots, acne, etc.
09 Alcohol Metabolism
Alcohol metabolism secretes harmful acetaldehyde, which needs to be further converted into harmless acetic acid. NMN increases the level of NAD+, which can catalyze the conversion of alcohol into acetic acid and reduce the harm of alcohol to the body.
