At 1:00 pm local time on August 24, the Japanese government ignored strong doubts and opposition from the international community and unilaterally initiated the discharge of contaminated water from the Fukushima nuclear accident into the sea. NMN
Since the Great East Japan Earthquake and Tsunami damaged the Fukushima Daiichi Nuclear Power Plant in March 2011, 1.34 million tons of nuclear-contaminated water has accumulated in its plant, which is expected to continue to be discharged within 30 years.
This incident has aroused concerns and heated discussions around the world, and the radiation issue has become the focus of attention.
“It is extremely irresponsible for the future of humanity that Japan brazenly discharges nuclear-contaminated water into the sea” (International Viewpoint)
This discharge involves the radiation of radioactive material, mainly from radioactive material produced during nuclear reactions and used in cooling and remedial operations following a nuclear accident.
Specifically, these radioactive substances may include radioactive iodine, radioactive cesium, radioactive hydrogen, etc. Among them, radioactive cesium and radioactive iodine are the two most common radioactive substances in normal operation and accidents of nuclear power plants.
Nuclear radiation is an invisible and intangible substance that can cause great harm to the human body. It mainly causes damage to human DNA and cells through the release of three high-energy particles, α, β, and γ. These particles can pass through human cells and destroy the double helix structure of DNA, causing serious consequences such as gene mutation and cell death.
Long-term exposure to nuclear radiation will increase the risk of cancer, reproductive system damage, and decreased immunity.
NMN can directly repair DNA damage caused by radiation exposure or aging
In the 2017 iTech competition, Professor David Sinclair, Ph.D. from Harvard Medical School, relied on his solution to a biological problem – NAD+ precursor NMN can directly repair DNA damage caused by radiation exposure or aging. Month has won NASA awards.
NMN an inherent metabolite of the human body, which can directly converted into the key coenzyme NAD+, so NMN is the precursor of NAD,
and its main function is to serve as an intermediate in the biosynthesis of NAD+ in the human body. NAD+ is an indispensable substance for nearly half of the body’s metabolic activities, but it declines rapidly with age. Therefore, taking NMN can increase the level of NAD+,
so that the energy level and gene repair ability of cells can restored to a better state.
When Professor David Sinclair treated mice with NAD+ and nicotinamide mononucleotide (NMN), their cells ability to repair DNA damage caused by radiation exposure or aging improved.
During astronauts missions to space, the astronauts exposed to radiation from the universe,
which can tens or even hundreds of times more than the amount of radiation we receive in our daily lives,
resulting in a very high probability of DNA damage in the astronauts bodies. Studies have shown that after a 4-year round-trip into the universe,
high-energy particles in space can cause 5% of the body’s cells to die and cause significant aging, and almost 100% of them will suffer from cancer.
The National Academy of Sciences of China confirms that NMN can enhance the body’s resistance to radiation
NAD+ precursor NMN can directly repair DNA damage caused by radiation exposure or aging,
so NASA also chooses NAD+ precursor NMN for astronauts’ radiation resistance. Radiation not only a problem faced by astronauts,
many practitioners related to radiation abroad will actively supplement NMN to resist aging. For example, relevant scientific research personnel (hardware engineers), pilots, flight attendants,
trapezemen who travel frequently, and outdoor workers who often exposed to the sun.
In addition, the research report of the Chinese National Academy of Sciences also pointed out that NMN can enhance the body’s resistance to radiation and has a positive effect on preventing radiation-induced diseases.
NMN improves NRF2 trapping cells and small radiation damage by regulating SIRT6 and SIRT7
Researchers from Peking Union Medical College Medical College published an article in “Free Radical Biology and Medicine”. Experiments showed that ionizing radiation activates NRF2, and the lack of NRF2 promotes cell senescence,
while inhibiting the levels of all proteins in the sirtuins family, including the expression of SIRT1-SIRT7. The final study showed that NMN may protect NRF2 KO cells from free radical damage by activating SIRT6 and SIRT7,
and supplementing NMN improved radiation-induced intestinal damage in NRF2-deficient mice.
NMN is a key cellular repair substance that protects DNA from radiation damage. The main mechanism of action is that NMN can stimulate the expression of Sirtuins gene family, thereby repairing damaged DNA and inhibiting cell apoptosis.
In addition, NMN can also enhance the antioxidant capacity of cells and reduce the damage of radiation to cells. Facing the threat of radiation, NMN provides us with a strong line of defense.
If you care about your own health, especially when facing a radiation environment,
you hope to add an extra protection for the health of yourself and your family,
take preventive measures against radiation in advance, be more prepared, and have more peace of mind.
